BDBM563512 8-(2-amino-6-((R)-1-(4- chloro-2-(3-methyl-1H- pyrazole-1-yl)phenyl)- 2,2,2- trifluoroethoxy)pyrimidine- 4-yl)-2- azaspiro[4.5]dec-7-ene- 3-carboxylic acid hydrochloride::US11407763, Example 79::US11407763, Example 80
SMILES Cc1ccn(n1)-c1cc(Cl)ccc1[C@@H](Oc1cc(nc(N)n1)C1=CCC2(CNC(C2)C(O)=O)CC1)C(F)(F)F
InChI Key InChIKey=YGTXHLVARBZIHQ-WRVMZKTCSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 563512
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Gwangju Institute of Science and Technology
US Patent
Gwangju Institute of Science and Technology
US Patent
Affinity DataIC50: 194nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Gwangju Institute of Science and Technology
US Patent
Gwangju Institute of Science and Technology
US Patent
Affinity DataIC50: 185nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair