BDBM563512 8-(2-amino-6-((R)-1-(4- chloro-2-(3-methyl-1H- pyrazole-1-yl)phenyl)- 2,2,2- trifluoroethoxy)pyrimidine- 4-yl)-2- azaspiro[4.5]dec-7-ene- 3-carboxylic acid hydrochloride::US11407763, Example 79::US11407763, Example 80

SMILES Cc1ccn(n1)-c1cc(Cl)ccc1[C@@H](Oc1cc(nc(N)n1)C1=CCC2(CNC(C2)C(O)=O)CC1)C(F)(F)F

InChI Key InChIKey=YGTXHLVARBZIHQ-WRVMZKTCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563512   

TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563512(8-(2-amino-6-((R)-1-(4- chloro-2-(3-methyl-1H- pyr...)
Affinity DataIC50:  194nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563512(8-(2-amino-6-((R)-1-(4- chloro-2-(3-methyl-1H- pyr...)
Affinity DataIC50:  185nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent