BDBM563572 N-[4-(2-{2-[3-(5-Cyclopropyl-2- fluoro-phenyl)-ureido]-thiazol-5- yl}-ethyl)-pyridin-2-yl]- acetamide::US11407771, Compound 398

SMILES CC(=O)Nc1cc(CCc2cnc(NC(=O)Nc3cc(ccc3F)C3CC3)s2)ccn1

InChI Key InChIKey=HPAQLJDXOORFHL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563572   

TargetMitogen-activated protein kinase 13(Human)
Washington University

US Patent
LigandPNGBDBM563572(US11407771, Compound 398 | N-[4-(2-{2-[3-(5-Cyclop...)
Affinity DataIC50: 250nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Washington University

US Patent
LigandPNGBDBM563572(US11407771, Compound 398 | N-[4-(2-{2-[3-(5-Cyclop...)
Affinity DataIC50: 1.00E+4nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
US Patent