BDBM564031 US11414384, Example 66 Isomer 1

SMILES Cn1cc(-c2ccc3c(C(=O)[C@H](NCCc4ccc(S(N)(=O)=O)cc4)c4ccccc4)c[nH]c3c2)cn1

InChI Key InChIKey=JHNYAHKUHMLTKC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 564031   

TargetHistone acetyltransferase p300 [1287-1666]/Histone acetyltransferase type B catalytic subunit(Human)
Constellation Pharmaceuticals

US Patent

LigandBDBM564031(US11414384, Example 66 Isomer 1)Copy SMILESCopy InChI

Affinity DataIC50: 960nMAssay Description:The p300 HAT domain (residues 1287-1666) was expressed and purified with an N-terminal His tag from Escherichia coli cells. The expressed protein was...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/30/2022
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL