BDBM564195 US11414384, Example 104 Isomer 1::US11414384, Example 83 Isomer 2

SMILES Cn1cc(-c2ccc3c(C(=O)[C@@H](NCCc4ccc(Cl)cc4)c4ccccc4)c[nH]c3c2)cn1

InChI Key InChIKey=PREKJLYPZPHGBS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 564195   

LigandChemical structure of BindingDB Monomer ID 564195BDBM564195(US11414384, Example 83 Isomer 2 | US11414384, Exam...)
Affinity DataIC50: 247nMAssay Description:The p300 HAT domain (residues 1287-1666) was expressed and purified with an N-terminal His tag from Escherichia coli cells. The expressed protein was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 564195BDBM564195(US11414384, Example 83 Isomer 2 | US11414384, Exam...)
Affinity DataIC50: 5.00E+3nMAssay Description:The p300 HAT domain (residues 1287-1666) was expressed and purified with an N-terminal His tag from Escherichia coli cells. The expressed protein was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent