BDBM564280 US11414384, Example 100 Isomer 1

SMILES Cn1cc(cn1)-c1ccn2c(cnc2c1)C(=O)[C@@H](NCCc1ccc(cc1)C#N)c1ccccc1

InChI Key InChIKey=RYPHRIMKBWOBND-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 564280   

TargetHistone acetyltransferase p300 [1287-1666]/Histone acetyltransferase type B catalytic subunit(Human)
Constellation Pharmaceuticals

US Patent

LigandBDBM564280(US11414384, Example 100 Isomer 1)Copy SMILESCopy InChI

Affinity DataIC50: 368nMAssay Description:The p300 HAT domain (residues 1287-1666) was expressed and purified with an N-terminal His tag from Escherichia coli cells. The expressed protein was...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/30/2022
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL