BDBM564457 US11414384, Example 132 Isomer 2

SMILES OC(=O)c1ccc(CCN[C@@H](C(=O)c2c[nH]c3ccccc23)c2ccccc2)cc1

InChI Key InChIKey=HXHMRYUSFNGAPA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 564457   

TargetHistone acetyltransferase p300 [1287-1666]/Histone acetyltransferase type B catalytic subunit(Human)
Constellation Pharmaceuticals

US Patent

LigandBDBM564457(US11414384, Example 132 Isomer 2)Copy SMILESCopy InChI

Affinity DataIC50: 1.79E+4nMAssay Description:The p300 HAT domain (residues 1287-1666) was expressed and purified with an N-terminal His tag from Escherichia coli cells. The expressed protein was...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/30/2022
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL