BDBM568039 US11420970, Example 241

SMILES COc1ccc(cc1)-c1cc(Cn2cnc3c(N)ncnc23)c(cn1)N1CCC[C@@](N)(C1)c1ccc(F)c(C)n1

InChI Key InChIKey=AOVWWKOOJQGEKX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 568039   

TargetHistone-lysine N-methyltransferase NSD2(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 568039BDBM568039(US11420970, Example 241)
Affinity DataIC50: 525nMAssay Description:This assay employed LC-MS/MS technology to monitor the SAH production from the NSD2 enzymatic reaction. The enzymatic reaction was performed in white...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent