BDBM568101 US11420970, Example 303

SMILES COc1ccc(cc1F)-c1cc(Cn2cnc3c(N)ncnc23)c(cn1)N1CCC[C@](N)(CC(F)(F)F)C1

InChI Key InChIKey=KONFTSZTQMVPLD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 568101   

TargetHistone-lysine N-methyltransferase NSD2(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 568101BDBM568101(US11420970, Example 303)
Affinity DataIC50: 525nMAssay Description:This assay employed LC-MS/MS technology to monitor the SAH production from the NSD2 enzymatic reaction. The enzymatic reaction was performed in white...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
US Patent