BDBM569653 N-((3R,4S)-3-Fluoro-1- (methylsulfonyl)piperidin- 4-yl)-4-(1-(3- fluoropyridin-4-yl)-2- methyl-1H-imidazol-4- yl)-5- (trifluoromethyl)pyrimidin- 2-amine::US11427567, Example 298

SMILES Cc1nc(cn1-c1ccncc1F)-c1nc(N[C@H]2CCN(C[C@H]2F)S(C)(=O)=O)ncc1C(F)(F)F

InChI Key InChIKey=XPVFRXAYPYIQPM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 569653   

LigandPNGBDBM569653(US11427567, Example 298 | N-((3R,4S)-3-Fluoro-1- (...)
Affinity DataIC50: 50nMAssay Description:CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent