BDBM571202 2-chloro-5-{2-acetamidoimidazo[1,2- b]pyridazin-6-yl}-N-{1-[2-fluoro-5- (trifluoromethyl)phenyl]ethyl}pyridine- 3-carboxamide::US11440913, Example 269::US11440913, Example 270

SMILES CC(NC(=O)c1cc(cnc1Cl)-c1ccc2nc(NC(C)=O)cn2n1)c1cc(ccc1F)C(F)(F)F

InChI Key InChIKey=GYKLZIYAECFALP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 571202   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM571202(US11440913, Example 270 | 2-chloro-5-{2-acetamidoi...)
Affinity DataIC50: 23nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM571202(US11440913, Example 270 | 2-chloro-5-{2-acetamidoi...)
Affinity DataIC50: 55nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent