BDBM574643 US11458149, Compound I-341 isomer 1

SMILES Cn1cnc(c1)-c1ccc(cc1Nc1cccc(c1)C(F)(F)F)[C@H]1CC(Br)=NO1

InChI Key InChIKey=IKTHDXLXNBGLSW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 574643   

TargetTranscriptional enhancer factor TEF-1(Human)
Ikena Oncology

US Patent
LigandPNGBDBM574643(US11458149, Compound I-341 isomer 1)
Affinity DataEC50: <100nMAssay Description:TEAD inhibition can be assayed using Hippo Pathway TEAD Reporter MCF7 Cell Line (BPS Bioscience, Catalog #: 60618).More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent