BDBM57497 4,4'-{[1-(3,4-dichlorobenzyl)-1H-indol-3-yl]methylene}bis(3-methyl-1H-pyrazol-5-ol)::4-[[1-(3,4-dichlorobenzyl)indol-3-yl]-(3-keto-5-methyl-3-pyrazolin-4-yl)methyl]-5-methyl-3-pyrazolin-3-one::4-[[1-[(3,4-dichlorophenyl)methyl]-3-indolyl]-(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-5-methyl-1,2-dihydropyrazol-3-one::4-[[1-[(3,4-dichlorophenyl)methyl]indol-3-yl]-(3-methyl-5-oxidanylidene-1,2-dihydropyrazol-4-yl)methyl]-5-methyl-1,2-dihydropyrazol-3-one::4-[[1-[(3,4-dichlorophenyl)methyl]indol-3-yl]-(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-5-methyl-1,2-dihydropyrazol-3-one::MLS000577401::SMR000197511::cid_2929846

SMILES Cc1[nH][nH]c(=O)c1C(c1cn(Cc2ccc(Cl)c(Cl)c2)c2ccccc12)c1c(C)[nH][nH]c1=O

InChI Key InChIKey=BFNOZDAIYYYRGE-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 57497   

TargetSentrin-specific protease 8(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM57497(4,4'-{[1-(3,4-dichlorobenzyl)-1H-indol-3-yl]me...)
Affinity DataIC50: 6.19E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetSentrin-specific protease 8(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM57497(4,4'-{[1-(3,4-dichlorobenzyl)-1H-indol-3-yl]me...)
Affinity DataIC50: 6.19E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM57497(4,4'-{[1-(3,4-dichlorobenzyl)-1H-indol-3-yl]me...)
Affinity DataEC50:  1.01E+4nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM57497(4,4'-{[1-(3,4-dichlorobenzyl)-1H-indol-3-yl]me...)
Affinity DataEC50:  2.70E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay