BDBM575932 2-(5-{3-[endo-3-amino- 8-azabicyclo[3.2.1]oc- tan-8-yl]-5H-pyrrolo [2,3-b]pyrazin-7-yl}-4- chloro-2H-indazol-2-yl)- N-tert-butylacetamide::US11466016, Example 60

SMILES CC(C)(C)NC(=O)Cn1cc2c(Cl)c(ccc2n1)-c1c[nH]c2nc(cnc12)N1[C@H]2CC[C@@H]1C[C@H](N)C2

InChI Key InChIKey=SFJRJQKPSCEFEF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575932   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM575932(US11466016, Example 60 | 2-(5-{3-[endo-3-amino- 8-...)
Affinity DataIC50: 12nMAssay Description:SHP2 activity was monitored by measuring the conversion of the surrogate substrate 6,8-difluoromethylumbelliferyl phosphate (DiFMUP) to the fluoresce...More data for this Ligand-Target Pair
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Date in BDB:
12/11/2022
Entry Details
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