BDBM578448 US11479533, Example 34::methyl 4-(2-((4-(1H-pyrazol-4-yl)phenyl)amino)-1-(methylamino)-2-oxoethyl)benzoate

SMILES CNC(C(=O)Nc1ccc(cc1)-c1cn[nH]c1)c1ccc(cc1)C(=O)OC

InChI Key InChIKey=BLWDQSNYRISVMN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 578448   

TargetRho-associated protein kinase 2 [1-552](Human)
Kadmon

US Patent
LigandPNGBDBM578448(methyl 4-(2-((4-(1H-pyrazol-4-yl)phenyl)amino)-1-(...)
Affinity DataIC50: 310nMAssay Description:Compounds activities were measured by Z'-lyte kinase kit (ThermoFisher Scientific). The percent inhibition rate was calculated by normalizing the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent