BDBM579039 2-(5-(4-(aminomethyl)-1-oxo-1,2-dihydrophthalazin- 6-yl)pyridin-3-yl)terephthalonitrile::US11479551, Example 8-9::US11492351, Example 8-9

SMILES NCc1n[nH]c(=O)c2ccc(cc12)-c1cncc(c1)-c1cc(ccc1C#N)C#N

InChI Key InChIKey=MXEGJBVYARIKTJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 579039   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Mirati Therapeutics

US Patent
LigandPNGBDBM579039(US11492351, Example 8-9 | US11479551, Example 8-9 ...)
Affinity DataIC50: 1.00E+4nMAssay Description:The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Mirati Therapeutics

US Patent
LigandPNGBDBM579039(US11492351, Example 8-9 | US11479551, Example 8-9 ...)
Affinity DataIC50: 1.00E+4nMAssay Description:The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent