BDBM579083 US11479551, Example 12-6::US11492351, Example 12-6

SMILES Cn1cc(cn1)-c1ccc(C#N)c(c1)-c1c(cnn1C)-c1ccc2c(c1)c(CNC(=O)OC(C)(C)C)n[nH]c2=O

InChI Key InChIKey=OGQJMWXEIJCYHA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 579083   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Mirati Therapeutics

US Patent
LigandPNGBDBM579083(US11492351, Example 12-6 | US11479551, Example 12-...)
Affinity DataIC50: 730nMAssay Description:The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Mirati Therapeutics

US Patent
LigandPNGBDBM579083(US11492351, Example 12-6 | US11479551, Example 12-...)
Affinity DataIC50: 730nMAssay Description:The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent