BDBM579372 US11479560, Title WZ-II-252::US11479560, Title WZ-II-253

SMILES CC(c1ccc(C)cc1)n1c2cccnc2n(C(Cc2ccc(C)cc2)C(=O)N2CC(C2)C#N)c1=N

InChI Key InChIKey=WYTRELALXGTYAT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 579372   

TargetOrexin receptor type 2(Human)
University ff Texas System

US Patent
LigandPNGBDBM579372(US11479560, Title WZ-II-252 | US11479560, Title WZ...)
Affinity DataEC50: <1.00E+3nMAssay Description:HEK293 cells stably expressing OX2R are transfected with Gq alpha construct (6.4 ug per 10 cm dish) using Lipofectamine 3000 (ThermoFisher). 24 hours...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

TargetOrexin receptor type 2(Human)
University ff Texas System

US Patent
LigandPNGBDBM579372(US11479560, Title WZ-II-252 | US11479560, Title WZ...)
Affinity DataEC50:  1.50E+3nMAssay Description:HEK293 cells stably expressing OX2R are transfected with Gq alpha construct (6.4 ug per 10 cm dish) using Lipofectamine 3000 (ThermoFisher). 24 hours...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent