BDBM579833 N-[2- hydroxy- 3-(1,2,3,4- tetrahydro- iso- quinolin- 2- yl)propyl]- 4- phenyl-::US11485731, Example 1C

SMILES OC(CNC(=O)N1CCN(CC1)c1ccccc1)CN1CCc2ccccc2C1

InChI Key InChIKey=XFGROBBZTZGDFL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 579833   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Argonaut Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 579833BDBM579833(US11485731, Example 1C | N-[2- hydroxy- 3-(1,2,3,4...)
Affinity DataIC50: 1.24E+3nMAssay Description:A PRMT5 chemiluminescent assay was used to measure the IC50 activity of PRMT5 of the compounds of Examples 1A to 7 above. Biotinylated histone peptid...More data for this Ligand-Target Pair
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Date in BDB:
1/6/2023
Entry Details
US Patent