BDBM579859 N-[2- hydroxy- 3-(1,2,3,4- tetrahydro- isoquinolin- 2- yl)propyl]- 2,3,4,5-::US11485731, Example 1J

SMILES OC(CNC(=O)N1CCCCc2ccccc12)CN1CCc2ccccc2C1

InChI Key InChIKey=RHLNNSHIVBHLJO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 579859   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Argonaut Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 579859BDBM579859(US11485731, Example 1J | N-[2- hydroxy- 3-(1,2,3,4...)
Affinity DataIC50: 320nMAssay Description:A PRMT5 chemiluminescent assay was used to measure the IC50 activity of PRMT5 of the compounds of Examples 1A to 7 above. Biotinylated histone peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent