BDBM579904 4-(3- oxa-8- azabicyclo [3.2.1] octane- 8- carbonyl)- N-((R)-3- (3,4- dihydro-::US11485731, Example 1BE

SMILES O[C@H](CNC(=O)N1CCC(CC1)C(=O)N1C2CCC1COC2)CN1CCc2ccccc2C1

InChI Key InChIKey=KYOVWTVYHRQPLL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 579904   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Argonaut Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 579904BDBM579904(US11485731, Example 1BE | 4-(3- oxa-8- azabicyclo ...)
Affinity DataIC50: 3.08E+3nMAssay Description:A PRMT5 chemiluminescent assay was used to measure the IC50 activity of PRMT5 of the compounds of Examples 1A to 7 above. Biotinylated histone peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent