BDBM579968 3-(3,4- dihydro- isoquinolin- 2(1H)-yl)- 2-hydroxy- propyl 4- acetyl-1,4-::US11485731, Example 4V

SMILES CC(=O)N1CCCN(CC1)C(=O)OCC(O)CN1CCc2ccccc2C1

InChI Key InChIKey=PUYNETUBTBIPLW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 579968   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Argonaut Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 579968BDBM579968(US11485731, Example 4V | 3-(3,4- dihydro- isoquino...)
Affinity DataIC50: 3.89E+4nMAssay Description:A PRMT5 chemiluminescent assay was used to measure the IC50 activity of PRMT5 of the compounds of Examples 1A to 7 above. Biotinylated histone peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent