BDBM580706 US11492346, Example 46

SMILES COc1cc(Cn2cccn2)cc2onc(NS(=O)(=O)c3ccc(cc3)C(F)(F)F)c12

InChI Key InChIKey=BASMSSZXDMITCE-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 580706   

TargetHistone acetyltransferase KAT6A [507-778](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 580706BDBM580706(US11492346, Example 46)
Affinity DataKi:  13.1nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 580706BDBM580706(US11492346, Example 46)
Affinity DataKi:  32.9nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

TargetHistone acetyltransferase KAT7(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 580706BDBM580706(US11492346, Example 46)
Affinity DataKi:  1.03E+3nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent