BDBM580745 US11492346, Example 85

SMILES COc1ccc(c(C)c1F)S(=O)(=O)Nc1noc2cc(Cn3cccn3)cc(OC)c12

InChI Key InChIKey=CQVLUBBFXSDBAB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 580745   

TargetHistone acetyltransferase KAT6A [507-778](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 580745BDBM580745(US11492346, Example 85)
Affinity DataKi:  8.77nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 580745BDBM580745(US11492346, Example 85)
Affinity DataKi:  13.3nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

TargetHistone acetyltransferase KAT7(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 580745BDBM580745(US11492346, Example 85)
Affinity DataKi:  1.14E+3nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent