BDBM580916 5-(4-(4-chloro-3-(trifluoromethyl)phenoxy)- 6-morpholinopyridin-2-yl)pyrimidin-2- amine::US11492348, Compound 128::US11492348, Compound 132

SMILES Nc1ncc(cn1)-c1cc(Oc2ccc(Cl)c(c2)C(F)(F)F)cc(n1)N1CCOCC1

InChI Key InChIKey=UCCMLSZWESYKCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 580916   

LigandPNGBDBM580916(US11492348, Compound 128 | 5-(4-(4-chloro-3-(trifl...)
Affinity DataIC50: 1.22E+3nMAssay Description:Quantification of ATP to ADP conversion as a measure of PI3Kα activity. Active PI3Kα (Life Technologies), in the presence or absence of PI3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

LigandPNGBDBM580916(US11492348, Compound 128 | 5-(4-(4-chloro-3-(trifl...)
Affinity DataIC50: 1.21E+3nMAssay Description:Quantification of ATP to ADP conversion as a measure of PI3Kα activity. Active PI3Kα (Life Technologies), in the presence or absence of PI3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent