BDBM581770 US11512080, Compound I-92

SMILES FC(F)(F)c1cc(SC2CCC(=O)NC2=O)cc(c1)C(F)(F)F

InChI Key InChIKey=UOTZIHJEPLOJNI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581770   

TargetProtein cereblon(Human)
Kymera Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 581770BDBM581770(US11512080, Compound I-92)
Affinity DataIC50: 5.50E+4nMAssay Description:Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent