BDBM582995 US11548892, Compound 121

SMILES COC(=O)N[C@@H](CC\C=C\C(N)=O)C(=O)Nc1cccn(Cc2nc3c(OC(C)C)cccc3[nH]2)c1=O

InChI Key InChIKey=MJIZJOWCYBVHLR-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 582995   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Sitari Pharma

US Patent

LigandBDBM582995(US11548892, Compound 121)Copy SMILESCopy InChI

Affinity DataIC50: 500nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/6/2023
Entry Details
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