BDBM583006 US11548892, Compound 132

SMILES CN(C)C(=O)O[C@@H](CC\C=C\C(=O)N(C)C)C(=O)Nc1cccn(Cc2nc3cc(F)cc(OCc4ccc(F)cc4F)c3[nH]2)c1=O

InChI Key InChIKey=LEGXCHPOROGKQH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 583006   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Sitari Pharma

US Patent

LigandBDBM583006(US11548892, Compound 132)Copy SMILESCopy InChI

Affinity DataIC50: 500nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/6/2023
Entry Details
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