BDBM585584 6-[3-(Difluoromethyl)-4-fluoro-phenyl]-3-methyl-1-(3- pyridylmethyl)pyrazolo[4,3-b]pyridine::US11530210, Example 199

SMILES Cc1nn(Cc2cccnc2)c2cc(cnc12)-c1ccc(F)c(c1)C(F)F

InChI Key InChIKey=FGASVXTXUKZODA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 585584   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM585584(US11530210, Example 199 | 6-[3-(Difluoromethyl)-4-...)
Affinity DataIC50: 34nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
Go to US Patent