BDBM589758 US11559538, Example 189::US11559538, Example 21::US11559538, Example 53

SMILES CCOc1cc(ccc1OC)-c1cncc(C2COB(O)C2)c1C

InChI Key InChIKey=PBCDQTPZNZNWEJ-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 589758   

TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 189 | US11559538, Example 21 |...)
Affinity DataIC50:  2.61nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 189 | US11559538, Example 21 |...)
Affinity DataIC50:  1.46E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 189 | US11559538, Example 21 |...)
Affinity DataIC50:  7.72nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterferon gamma receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 189 | US11559538, Example 21 |...)
Affinity DataIC50:  1.46nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 189 | US11559538, Example 21 |...)
Affinity DataIC50:  0.640nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterferon gamma receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 189 | US11559538, Example 21 |...)
Affinity DataIC50:  0.600nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 189 | US11559538, Example 21 |...)
Affinity DataIC50:  0.840nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterferon gamma receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 189 | US11559538, Example 21 |...)
Affinity DataIC50:  1.35nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 189 | US11559538, Example 21 |...)
Affinity DataIC50:  1.41nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 189 | US11559538, Example 21 |...)
Affinity DataIC50:  115nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 189 | US11559538, Example 21 |...)
Affinity DataIC50:  4.87nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589758(US11559538, Example 189 | US11559538, Example 21 |...)
Affinity DataIC50:  159nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent