BDBM589952 US11559538, Example 199

SMILES CCOc1c(OC)ccc(c1F)-c1cccc(n1)C1COB(O)C1

InChI Key InChIKey=VAYIZKDIBKDBHR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 589952   

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589952(US11559538, Example 199)
Affinity DataIC50: 4.55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

LigandPNGBDBM589952(US11559538, Example 199)
Affinity DataIC50: 10.4nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589952(US11559538, Example 199)
Affinity DataIC50: 90.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589952(US11559538, Example 199)
Affinity DataIC50: 1.59E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent