BDBM591203 5-(8-amino-7-fluoro-3-((6-isopropyl-7- oxo-5,6,7,8-tetrahydro-4H-pyrazolo[1,5- d][1,4]diazepin-2-yl)amino)isoquinolin- 6-yl)-1-ethyl-1H-pyrazole-3-carbonitrile::US11566003, Compound 269

SMILES CCn1nc(cc1-c1cc2cc(Nc3cc4CCN(C(C)C)C(=O)Cn4n3)ncc2c(N)c1F)C#N

InChI Key InChIKey=REYRYOWVPMLROG-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 591203   

LigandPNGBDBM591203(5-(8-amino-7-fluoro-3-((6-isopropyl-7- oxo-5,6,7,8...)
Affinity DataKi:  8.80nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent