BDBM592254 6-(3-cyanopyrrolo[1,2- b]pyridazin-7-yl)-N-((R)-2-fluoro- 3-hydroxy-3-methylbutyl)-4- (((1r,4R)-4-(4-(oxetan-3-yl)-1H- 1,2,3-triazol-1- yl)cyclohexyl)amino)nicotinamide::US11572362, Compound 33

SMILES CC(C)(O)[C@H](F)CNC(=O)c1cnc(cc1N[C@H]1CC[C@@H](CC1)n1cc(nn1)C1COC1)-c1ccc2cc(cnn12)C#N

InChI Key InChIKey=GJSVNWNZQQFSDS-UMQWNRPGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 592254   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM592254(6-(3-cyanopyrrolo[1,2- b]pyridazin-7-yl)-N-((R)-2...)
Affinity DataIC50:  1nMAssay Description:The enzyme and peptide solution were incubated with compound for 15 minutes at room temp before the reaction was initiated by the addition of ATP. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent