BDBM592569 Mixture of two diastereomers: (3R)-1-(3- chlorophenyl)-N-(7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-5-oxo-3- pyrrolidinecarboxamide, and (3S)-1-(3- chlorophenyl)-N-(7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-5-oxo-3- pyrrolidinecarboxamide::US11572374, Example 1-61

SMILES Clc1cccc(c1)N1C[C@H](CC1=O)C(=O)N[C@@H]1C[C@@H]2CC[C@H]1N2C#N

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 592569   

LigandPNGBDBM592569(Mixture of two diastereomers: (3R)-1-(3- chlorophe...)
Affinity DataIC50: 1.20E+3nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent