BDBM592571 Mixture of two diastereomers: (3R)-1-(3- chlorophenyl)-N-(7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-2-oxo-3- pyrrolidinecarboxamide, and (3S)-1-(3- chlorophenyl)-N-(7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-2-oxo-3- pyrrolidinecarboxamide::US11572374, Example 1-63

SMILES Clc1cccc(c1)N1CC[C@H](C(=O)N[C@@H]2C[C@@H]3CC[C@H]2N3C#N)C1=O

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 592571   

LigandPNGBDBM592571(Mixture of two diastereomers: (3R)-1-(3- chlorophe...)
Affinity DataIC50: 700nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent