BDBM592646 (4R)-7-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-2,3,4,5- tetrahydro-1-benzoxepine-4-carboxamide::US11572374, Example 1-69

SMILES Clc1ccc2OCCC(Cc2c1)C(=O)N[C@@H]1C[C@@H]2CC[C@H]1N2C#N

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 592646   

LigandPNGBDBM592646((4R)-7-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[...)
Affinity DataIC50: 2.32E+3nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
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Date in BDB:
3/26/2023
Entry Details
US Patent