BDBM594660 2-(2-Oxoindoline-4-carbonyl)-2,7-diazaspiro[4.5]decane-6,8-dione::US11584748, Example 27

SMILES O=C(N1CCC2(C1)CCC(=O)NC2=O)c1cccc2NC(=O)Cc12

InChI Key InChIKey=YAQOLPJWAQESJG-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 594660   

TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 594660BDBM594660(2-(2-Oxoindoline-4-carbonyl)-2,7-diazaspiro[4.5]de...)
Affinity DataKd:  47nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent