BDBM595605 US11591326, Compound 21

SMILES CC1Cc2ccc(NC3COC3)cc2C(=O)N1CC(O)CN1CCc2ccccc2C1

InChI Key InChIKey=BDFKEHMYAOSLHV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 595605   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Pharmablock Sciences (Nanjing)

US Patent
LigandChemical structure of BindingDB Monomer ID 595605BDBM595605(US11591326, Compound 21)
Affinity DataIC50: 480nMAssay Description:General Procedure for PRMT5/MEP50 AlphaLISA Enzyme Inhibitory Assays: Assays were performed in the buffer consisting of 50 mM Tris, pH 8.5, 5 mM MgCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
US Patent