BDBM595668 US11591328, Compound 21

SMILES Cn1cc(cn1)-c1cc(Oc2ccc(NC(=O)N3CCC4(CCC(F)(F)C4)C3=O)nc2)ccn1

InChI Key InChIKey=YESKHRZGFKDGEH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 595668   

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Xiamen Biotime Biotechnology

US Patent
LigandPNGBDBM595668(US11591328, Compound 21)
Affinity DataIC50:  2.80nMAssay Description:CSF1R: The specific operation is as follows: Set the concentration gradient of the test compound and dilute the test compound to the working concentr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Xiamen Biotime Biotechnology

US Patent
LigandPNGBDBM595668(US11591328, Compound 21)
Affinity DataIC50:  7.45E+3nMAssay Description:c-Kit, PDGFRα, PDGFRβ, FLT-3:Add 5 μL of compound (10% DMSO) at 5 times the final concentration of the reaction to a 384-well plate. A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Xiamen Biotime Biotechnology

US Patent
LigandPNGBDBM595668(US11591328, Compound 21)
Affinity DataIC50:  43nMAssay Description:c-Kit, PDGFRα, PDGFRβ, FLT-3:Add 5 μL of compound (10% DMSO) at 5 times the final concentration of the reaction to a 384-well plate. A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Xiamen Biotime Biotechnology

US Patent
LigandPNGBDBM595668(US11591328, Compound 21)
Affinity DataIC50:  10.1nMAssay Description:c-Kit, PDGFRα, PDGFRβ, FLT-3:Add 5 μL of compound (10% DMSO) at 5 times the final concentration of the reaction to a 384-well plate. A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent