BDBM595751 US11591331, Example 77

SMILES CNC(=O)c1ccc2c(n1)OC[C@@H]1CN(Cc3cnc4cc(C)c(=O)[nH]c4c3)CCN21

InChI Key InChIKey=LUEKTFALTSGELH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 595751   

TargetPoly [ADP-ribose] polymerase 1(Human)
Xinthera

US Patent
LigandChemical structure of BindingDB Monomer ID 595751BDBM595751(US11591331, Example 77)
Affinity DataIC50: 8.40nMAssay Description:Assays based on fluorescent polarization (FP) have been widely utilized in drug discovery due to the homogenous format, robust performance and lack o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Xinthera

US Patent
LigandChemical structure of BindingDB Monomer ID 595751BDBM595751(US11591331, Example 77)
Affinity DataIC50: 2.30E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
US Patent