BDBM595931 US11591336, Compound 398

SMILES C[C@@H]1OCC2(CCN(CC2)c2cnc3c(n[nH]c3n2)N2CCN(C3COC3)c3cc(ccc23)C#N)[C@@H]1N

InChI Key InChIKey=KMVWXRVMBLDRCR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 595931   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
D. E. Shaw Research

US Patent
LigandPNGBDBM595931(US11591336, Compound 398)
Affinity DataIC50: 1.00E+3nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
US Patent