BDBM596177 US11591336, Compound 220

SMILES C[C@@H]1OCC2(CCN(CC2)c2cnc3c(n[nH]c3n2)N2CC[C@H](C)c3cc(ccc23)C#N)[C@@H]1N

InChI Key InChIKey=PEMKJWVXUUUHOP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 596177   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
D. E. Shaw Research

US Patent
LigandPNGBDBM596177(US11591336, Compound 220)
Affinity DataIC50: 1.00E+3nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
US Patent