BDBM5979 6-(N-(tert-Butoxycarbonyl)-N-methylaminomethyl)-3-(methylthio)-1-(2,4,6-trichlorophenyl)-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one::pyrazolo[3,4-d]pyrimidin-4-one deriv. 17e::tert-butyl N-methyl-N-{[3-(methylsulfanyl)-4-oxo-1-(2,4,6-trichlorophenyl)-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-6-yl]methyl}carbamate

SMILES CSc1nn(-c2c(Cl)cc(Cl)cc2Cl)c2nc(CN(C)C(=O)OC(C)(C)C)[nH]c(=O)c12

InChI Key InChIKey=GYMRYPQUSLJQRM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5979   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Bristol-Myers Squibb

LigandPNGBDBM5979(6-(N-(tert-Butoxycarbonyl)-N-methylaminomethyl)-3-...)
Affinity DataIC50: 5.00E+4nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2005
Entry Details Article
PubMed