BDBM597945 US11608347, Example 63-B::[(7S,9aS)-7-(3-chloro-4- fluorophenyl)- 1,3,4,6,7,8,9,9a- octahydropyrido[1,2- a]pyrazin-2-yl]-(4- chlorothieno[2,3-b]pyridin-5- yl)methanone

SMILES Fc1ccc(cc1Cl)[C@@H]1CC[C@H]2CN(CCN2C1)C(=O)c1cnc2sccc2c1Cl

InChI Key InChIKey=NAZIMAGMDOMRRA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 597945   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM597945(US11608347, Example 63-B | [(7S,9aS)-7-(3-chloro-4...)
Affinity DataIC50: 17.5nMAssay Description:In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...More data for this Ligand-Target Pair
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Date in BDB:
5/5/2023
Entry Details
US Patent