BDBM599035 5-[4-amino-5- (trifluoromethyl) pyrrolo[2,1- f][1,2,4]triazin- 7-yl]-2-methyl- N-(3- phenylbutyl) pyridine-3- carboxamide::US11618753, Example 171::US11618753, Example 275

SMILES CC(CCNC(=O)c1cncc(c1)-c1cc(c2c(N)ncnn12)C(F)(F)F)c1ccccc1

InChI Key InChIKey=LSDPJYFXTQINDK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 599035   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM599035(US11618753, Example 275 | 5-[4-amino-5- (trifluoro...)
Affinity DataIC50: 2.40E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM599035(US11618753, Example 275 | 5-[4-amino-5- (trifluoro...)
Affinity DataIC50: 1.20E+4nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
Go to US Patent