BDBM600124 5-[4-amino-5-(trifluoromethyl)- pyrrolo[2,1-f][1,2,4]triazin-7- yl]-N-[(3R,4S)-4-fluoro-1-(3- hydroxy-3-methylbutan-2-yl)- pyrrolidin-3-yl]-2-methoxy- pyridine-3-carboxamide::US11618753, Example 1407::US11618753, Example 1415

SMILES COc1ncc(cc1C(=O)N[C@@H]1CN(C[C@@H]1F)C(C)C(C)(C)O)-c1cc(c2c(N)ncnn12)C(F)(F)F

InChI Key InChIKey=ARADQEJMNYAUGQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 600124   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM600124(US11618753, Example 1407 | 5-[4-amino-5-(trifluoro...)
Affinity DataIC50: 3.80E+4nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM600124(US11618753, Example 1407 | 5-[4-amino-5-(trifluoro...)
Affinity DataIC50: 7.80E+4nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
Go to US Patent