BDBM601231 (S)-3-(((S)-4,4-dimethyl-3-phenylpentanamido)methyl)-N,2-dimethyl-1,2,3,4-tetrahydroisoquinoline-7-carboxamide ::US11634396, Compound 168

SMILES CNC(=O)c1ccc2C[C@@H](CNC(=O)C[C@H](c3ccccc3)C(C)(C)C)N(C)Cc2c1

InChI Key InChIKey=JJZQXUFKQNFNIQ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 601231   

TargetDelta-type opioid receptor(Human)
Epiodyne

US Patent
LigandPNGBDBM601231(US11634396, Compound 168 | (S)-3-(((S)-4,4-dimethy...)
Affinity DataEC50: <300nMAssay Description:The dOR cAMP agonist and antagonist assays were conducted in a manner similar as described above for the mOR assays using CHO Tag-lite human dOR stab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
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TargetMu-type opioid receptor(Human)
Epiodyne

US Patent
LigandPNGBDBM601231(US11634396, Compound 168 | (S)-3-(((S)-4,4-dimethy...)
Affinity DataIC50: 1.65E+3nMAssay Description:CHO Tag-lite human mOR stable cell line from Cisbio (NCBI accession number: NM_000914.3, Bedford, Mass.) were seeded and grown to approximately 80% c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2023
Entry Details
Go to US Patent