BDBM602117 US11643417, Ex. No. 129::US11643417, Ex. No. 142

SMILES FC(F)(F)c1ccc2oc3c(N(CCC4COC(CC#N)CO4)CCNC3=O)c2c1

InChI Key InChIKey=WZTGLTINNLZODQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 602117   

TargetSerine/threonine-protein kinase pim-1(Human)
Japan Tobacco

US Patent
LigandPNGBDBM602117(US11643417, Ex. No. 129 | US11643417, Ex. No. 142)
Affinity DataKi:  1.18nMAssay Description:The calculation of the Pim-1 inhibitory activity of the compound was performed using the following solution according to the protocol attached to ADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Japan Tobacco

US Patent
LigandPNGBDBM602117(US11643417, Ex. No. 129 | US11643417, Ex. No. 142)
Affinity DataKi:  4.40nMAssay Description:The calculation of the Pim-1 inhibitory activity of the compound was performed using the following solution according to the protocol attached to ADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
Go to US Patent