BDBM602172 US11643417, Ex. No. 2-01

SMILES CC1(C)OC[C@]2(CC[C@H](CCN3CCNC(=O)c4oc5ccc(cc5c34)C(F)(F)F)CC2)O1

InChI Key InChIKey=DRFRWMPUXDRBPC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602172   

TargetSerine/threonine-protein kinase pim-1(Human)
Japan Tobacco

US Patent
LigandPNGBDBM602172(US11643417, Ex. No. 2-01)
Affinity DataKi:  1.60nMAssay Description:The calculation of the Pim-1 inhibitory activity of the compound was performed using the following solution according to the protocol attached to ADP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2023
Entry Details
Go to US Patent