BDBM602743 (5Z)-5-[[1-(3-pyridyl)pyrazol-4-yl]methylene]thiazolidine-2,4-dione::US11649231, Example 1-52

SMILES O=C1NC(=O)\C(S1)=C\c1cnn(c1)-c1cccnc1

InChI Key InChIKey=XMXAXBIESVYSIC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 602743   

TargetSerine/threonine-protein kinase mTOR(Human)
Medicinal Bioconvergence Research Center

US Patent
LigandPNGBDBM602743(US11649231, Example 1-52 | (5Z)-5-[[1-(3-pyridyl)...)
Affinity DataIC50: 93.4nMAssay Description:Among the compounds of the Examples 1-1 to 1-61, compounds that showed excellent inhibitory activity (inhibitory activity of 85% or more at 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent