BDBM604018 US11660293, Example 121

SMILES C[C@H]1C2CC(C2)N(C1COc1ccc(F)cc1)C(=O)c1nc(C)sc1-c1cnccn1

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 604018   

TargetOrexin/Hypocretin receptor type 1(Human)
Chronos Therapeutics

US Patent
LigandPNGBDBM604018(US11660293, Example 121)
Affinity DataKi:  43.7nMAssay Description:CHO cells stably transfected with human Orexin type 1 receptors (CHO-hOX1) or HEK-293 cells transiently transfected with human Orexin type 2 receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Chronos Therapeutics

US Patent
LigandPNGBDBM604018(US11660293, Example 121)
Affinity DataKi:  2.88E+3nMAssay Description:CHO cells stably transfected with human Orexin type 1 receptors (CHO-hOX1) or HEK-293 cells transiently transfected with human Orexin type 2 receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
US Patent